6ZPI
Microtubule complexed with Kif15 motor domain. Symmetrised asymmetric unit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Kinesin-like protein KIF15 | polymer | 377 | 41157.1 | 1 | UniProt (Q9NS87) Pfam (PF00225) | Homo sapiens (Human) | Kinesin-like protein 2,hKLP2,Kinesin-like protein 7,Serologically defined breast cancer antigen NY-BR-62 |
| 2 | B (A) | Tubulin alpha-1B chain | polymer | 437 | 48679.1 | 1 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (Pig) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 3 | C (B) | Tubulin beta chain | polymer | 431 | 48299.3 | 1 | UniProt (P02554) Pfam (PF00091) Pfam (PF03953) | Sus scrofa (Pig) | Beta-tubulin |
| 4 | D (C) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | E, G (C, A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) PubChem (888) | |||
| 6 | F (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 7 | H (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 8 | I (B) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) PubChem (16757828) PubChem (16760674) PubChem (4666) PubChem (21458255) PubChem (23307219) PubChem (23412627) PubChem (23636632) PubChem (24848897) PubChem (24867246) PubChem (16760177) PubChem (16742549) PubChem (44323108) PubChem (44356961) PubChem (44403716) PubChem (21733096) PubChem (23307242) PubChem (23307253) PubChem (23307913) PubChem (24754091) PubChem (46781469) PubChem (24207713) PubChem (24791027) PubChem (49868078) PubChem (25200067) PubChem (54259298) PubChem (42613129) PubChem (42620039) PubChem (44155032) PubChem (44276363) PubChem (57908851) PubChem (57946364) PubChem (44279927) PubChem (44335735) PubChem (44291178) PubChem (44328863) PubChem (44342632) PubChem (44356895) PubChem (44378736) PubChem (58803237) PubChem (59844545) PubChem (45489039) PubChem (46782671) PubChem (59904698) PubChem (60123443) PubChem (71209844) PubChem (70943371) PubChem (71096818) PubChem (53313247) PubChem (53298534) PubChem (54259297) PubChem (54259299) PubChem (57489669) PubChem (73759783) PubChem (57999380) PubChem (58460861) PubChem (58777027) PubChem (58798493) PubChem (58596717) PubChem (59048611) PubChem (59042813) PubChem (58877402) PubChem (60005248) PubChem (59873251) PubChem (59914794) PubChem (59919147) PubChem (60123436) PubChem (60011010) PubChem (60147315) PubChem (66795656) PubChem (14060298) PubChem (176586897) PubChem (177678861) PubChem (36314) PubChem (60915) PubChem (177409) PubChem (184492) PubChem (70801836) PubChem (70842048) PubChem (70848451) PubChem (70856170) PubChem (441276) PubChem (73707502) PubChem (73759704) PubChem (89493063) PubChem (89847578) PubChem (90057663) PubChem (91122402) PubChem (91885464) PubChem (5460441) PubChem (5317123) PubChem (5321715) PubChem (101920282) PubChem (5352019) PubChem (121459571) PubChem (122361554) PubChem (6604028) PubChem (6604616) PubChem (6604814) PubChem (6713921) PubChem (6915727) PubChem (124747272) PubChem (124893098) PubChem (9875988) PubChem (126968948) PubChem (129395998) PubChem (129627423) PubChem (10748131) PubChem (132517454) PubChem (11320430) PubChem (11354895) PubChem (101598423) PubChem (134368714) PubChem (118528174) PubChem (134972678) PubChem (9854162) PubChem (9897470) PubChem (10033513) PubChem (137705323) PubChem (138106885) PubChem (10485732) PubChem (140731501) PubChem (140512017) PubChem (11506104) PubChem (11828953) PubChem (124747271) PubChem (124747273) PubChem (124747274) PubChem (14060299) PubChem (14060304) PubChem (14060306) PubChem (14060309) PubChem (146034004) PubChem (15983941) PubChem (153289350) PubChem (154037993) PubChem (155982214) PubChem (159121804) PubChem (160053861) PubChem (159716711) PubChem (160171678) PubChem (160585530) PubChem (163077211) PubChem (163077212) PubChem (163077209) PubChem (163284947) PubChem (126761000) PubChem (168322423) PubChem (169917882) PubChem (171036874) PubChem (175758871) PubChem (133052515) PubChem (133640187) PubChem (134715514) PubChem (143890766) PubChem (152743329) PubChem (154828192) PubChem (144453087) PubChem (160585532) PubChem (163077210) PubChem (163077213) PubChem (163077214) PubChem (163077215) PubChem (165084161) PubChem (166711459) PubChem (167423928) PubChem (170014955) PubChem (170362150) |
Sequence modifications
C: 1 - 374 (UniProt: Q9NS87)
A: 1 - 437 (UniProt: Q2XVP4)
| PDB | External Database | Details |
|---|---|---|
| Ser 5 | Cys 5 | conflict |
| Ser 50 | Cys 50 | conflict |
| Ser 162 | Cys 162 | conflict |
| Cys 250 | Ser 250 | conflict |
| Thr 294 | Cys 294 | conflict |
| Ser 314 | Cys 314 | conflict |
| Ser 346 | Cys 346 | conflict |
| Cys 375 | - | expression tag |
| Leu 376 | - | expression tag |
| Glu 377 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Thr 340 | Ser 340 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 138135.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2375.1 | |
| All* | Total formula weight | 140510.6 |
