6ZPI
Microtubule complexed with Kif15 motor domain. Symmetrised asymmetric unit
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C | Kinesin-like protein KIF15 | polymer | 377 | 41157.1 | 1 | UniProt (Q9NS87) Pfam (PF00225) In PDB | Homo sapiens (Human) | Kinesin-like protein 2,hKLP2,Kinesin-like protein 7,Serologically defined breast cancer antigen NY-BR-62 |
| 2 | A | Tubulin alpha-1B chain | polymer | 437 | 48679.1 | 1 | UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (Pig) | Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain |
| 3 | B | Tubulin beta chain | polymer | 431 | 48299.3 | 1 | UniProt (P02554) Pfam (PF00091) Pfam (PF03953) In PDB | Sus scrofa (Pig) | Beta-tubulin |
| 4 | C | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | C, A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | A | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 7 | B | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 8 | B | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) |
Sequence modifications
C: 1 - 374 (UniProt: Q9NS87)
A: 1 - 437 (UniProt: Q2XVP4)
| PDB | External Database | Details |
|---|---|---|
| Ser 5 | Cys 5 | conflict |
| Ser 50 | Cys 50 | conflict |
| Ser 162 | Cys 162 | conflict |
| Cys 250 | Ser 250 | conflict |
| Thr 294 | Cys 294 | conflict |
| Ser 314 | Cys 314 | conflict |
| Ser 346 | Cys 346 | conflict |
| Cys 375 | - | expression tag |
| Leu 376 | - | expression tag |
| Glu 377 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Thr 340 | Ser 340 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 138135.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2375.1 | |
| All* | Total formula weight | 140510.6 |
