6ZPI

Microtubule complexed with Kif15 motor domain. Symmetrised asymmetric unit

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (C)	Kinesin-like protein KIF15	polymer	377	41157.1	1	UniProt (Q9NS87) Pfam (PF00225)	Homo sapiens (Human)	Kinesin-like protein 2,hKLP2,Kinesin-like protein 7,Serologically defined breast cancer antigen NY-BR-62
2	B (A)	Tubulin alpha-1B chain	polymer	437	48679.1	1	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (Pig)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
3	C (B)	Tubulin beta chain	polymer	431	48299.3	1	UniProt (P02554) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (Pig)	Beta-tubulin
4	D (C)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
5	E, G (C, A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
6	F (A)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	1	Chemie (GTP)
7	H (B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
8	I (B)	TAXOL	non-polymer		853.9	1	Chemie (TA1)

Sequence modifications

C: 1 - 374 (UniProt: Q9NS87)

PDB	External Database	Details
Ser 5	Cys 5	conflict
Ser 50	Cys 50	conflict
Ser 162	Cys 162	conflict
Cys 250	Ser 250	conflict
Thr 294	Cys 294	conflict
Ser 314	Cys 314	conflict
Ser 346	Cys 346	conflict
Cys 375	-	expression tag
Leu 376	-	expression tag
Glu 377	-	expression tag

A: 1 - 437 (UniProt: Q2XVP4)

PDB	External Database	Details
Thr 340	Ser 340	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	138135.5
Non-Polymers*	Number of molecules	6
	Total formula weight	2375.1
All*	Total formula weight	140510.6

*Water molecules are not included.