6ZOT

Crystal structure of YTHDF3 YTH domain in complex with m6A RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, A)	YTH domain-containing family protein 3	polymer	199	23285.3	2	UniProt (Q7Z739) Pfam (PF04146)	Homo sapiens (Human)
2	C (C)	RNA	polymer	5	1600.0	1		Homo sapiens
3	D, E, F (B, A, C)	water	water		18.0	105	Chemie (HOH)

Sequence modifications

B, A: 392 - 571 (UniProt: Q7Z739)

PDB	External Database	Details
Met 373	-	initiating methionine
Gly 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag
His 380	-	expression tag
Ser 381	-	expression tag
Ser 382	-	expression tag
Gly 383	-	expression tag
Arg 384	-	expression tag
Glu 385	-	expression tag
Asn 386	-	expression tag
Leu 387	-	expression tag
Tyr 388	-	expression tag
Phe 389	-	expression tag
Gln 390	-	expression tag
Gly 391	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	48170.5
All*	Total formula weight	48170.5

*Water molecules are not included.