6ZN0
Crystal structure of cAMP-dependent protein kinase A (CHO PKA) in complex with isonicotinamidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cAMP-dependent protein kinase catalytic subunit alpha | polymer | 353 | 41113.8 | 1 | UniProt (P25321) Pfam (PF00069) In PDB | Cricetulus griseus (Chinese hamster) | PKA C-alpha |
| 2 | A | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) | |||
| 3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 4 | A | ISONICOTINAMIDINE | non-polymer | 121.1 | 2 | Chemie (NTN) | |||
| 5 | water | water | 18.0 | 265 | Chemie (HOH) |
Sequence modifications
A: 0 - 350 (UniProt: P25321)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| His -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41113.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 516.7 | |
| All* | Total formula weight | 41630.5 |
