6ZMN
Crystal structure of the Smad3-Smad5 MH1 domain chimera bound to the GGCGC site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Mothers against decapentaplegic homolog 3 | polymer | 125 | 14673.1 | 2 | UniProt (P84022) Pfam (PF03165) In PDB | Homo sapiens (Human) | hMAD-3,JV15-2,SMAD family member 3,hSMAD3 |
2 | C, D | DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP*GP*CP*A)-3') | polymer | 16 | 4900.2 | 2 | Homo sapiens | ||
3 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
5 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
6 | B | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
7 | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A, B: 10 - 133 (UniProt: P84022)
PDB | External Database | Details |
---|---|---|
Gly 9 | - | expression tag |
Ala 11 | Ile 11 | conflict |
Gln 20 | Lys 20 | conflict |
Asp 22 | Glu 22 | conflict |
Glu 23 | Gln 23 | conflict |
- | Asn 24 | deletion |
- | Gly 25 | deletion |
- | Gln 26 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 39146.6 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 402.1 | |
All* | Total formula weight | 39548.7 |