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6ZLN

CLK1 bound with GW807982X (Cpd 8)

Replaces:  6YTH
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dual specificity protein kinase CLK1polymer33939581.51UniProt (P49759)
Pfam (PF00069)
Homo sapiens (Human)CDC-like kinase 1
2B, C
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
3D
(A)
4-(6-ethoxypyrazolo[1,5-b]pyridazin-3-yl)-~{N}-[3-methoxy-5-(trifluoromethyl)phenyl]pyrimidin-2-aminenon-polymer430.41Chemie (PKB)
4E
(A)
waterwater18.0407Chemie (HOH)
Sequence modifications
A: 148 - 484 (UniProt: P49759)
PDBExternal DatabaseDetails
Ser 146-expression tag
Met 147-expression tag
Ala 432Arg 432conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39581.5
Non-Polymers*Number of molecules3
Total formula weight554.5
All*Total formula weight40136.0
*Water molecules are not included.

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PDB entries from 2025-12-17

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