6ZKX
Crystal structure of InhA:01 TCR in complex with HLA-E (Y84C) bound to InhA (53-61 GCG)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, alpha chain E | polymer | 277 | 31895.2 | 1 | UniProt (P13747) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (Human) | MHC class I antigen E |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | Enoyl-[acyl-carrier-protein] reductase [NADH] | polymer | 12 | 1197.5 | 1 | UniProt (P9WGR1) | Mycobacterium tuberculosis H37Rv | Enoyl-ACP reductase,FAS-II enoyl-ACP reductase,NADH-dependent 2-trans-enoyl-ACP reductase |
| 4 | D (D) | T-cell receptor alpha chain | polymer | 199 | 21496.7 | 1 | Homo sapiens (Human) | ||
| 5 | E (E) | T-cell receptor beta chain | polymer | 245 | 27491.5 | 1 | Homo sapiens (Human) | ||
| 6 | F, G, H, I, J... (A, B, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 7 | N, O, P, Q, R (A, B, C, D, E) | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence modifications
A: 1 - 276 (UniProt: P13747)
B: 3 - 101 (UniProt: P61769)
C: 1 - 12 (UniProt: P9WGR1)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Cys 84 | Tyr 105 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 2 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly 10 | Glu 62 | engineered mutation |
| Cys 11 | Leu 63 | engineered mutation |
| Gly 12 | Asp 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 93960.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 496.5 | |
| All* | Total formula weight | 94456.8 |
