6ZHY
Cryo-EM structure of the regulatory linker of ALC1 bound to the nucleosome's acidic patch: hexasome class.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, E | Histone H3 | polymer | 136 | 15403.1 | 2 | UniProt (A0A310TTQ1) Pfam (PF00125) UniProt (by SIFTS) (P84233) In PDB | Xenopus laevis (African clawed frog) | |
2 | B, F | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62799) Pfam (PF15511) In PDB | Xenopus laevis (African clawed frog) | |
3 | C | Histone H2A type 1 | polymer | 130 | 14109.4 | 1 | UniProt (P06897) Pfam (PF00125) Pfam (PF16211) In PDB | Xenopus laevis (African clawed frog) | |
4 | D | Histone H2B 1.1 | polymer | 123 | 13655.9 | 1 | UniProt (P02281) Pfam (PF00125) In PDB | Xenopus laevis (African clawed frog) | H2B1.1 |
5 | I | DNA (110-MER) Widom 601 sequence | polymer | 145 | 44520.4 | 1 | synthetic construct | ||
6 | J | DNA (110-MER) Widom 601 sequence | polymer | 145 | 44991.7 | 1 | synthetic construct | ||
7 | K | Chromodomain-helicase-DNA-binding protein 1-like | polymer | 37 | 4073.7 | 1 | UniProt (Q86WJ1) In PDB | Homo sapiens | Amplified in liver cancer protein 1 |
Sequence modifications
A, E: 0 - 135 (UniProt: A0A310TTQ1)
C: 0 - 129 (UniProt: P06897)
D: 1 - 122 (UniProt: P02281)
K: 604 - 639 (UniProt: Q86WJ1)
PDB | External Database | Details |
---|---|---|
Ala 110 | Cys 111 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Arg 99 | Gly 100 | conflict |
Ser 123 | Ala 124 | conflict |
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Thr 29 | Ser 33 | conflict |
PDB | External Database | Details |
---|---|---|
Lys 640 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 9 |
Total formula weight | 174946.1 | |
All* | Total formula weight | 174946.1 |