6ZGZ
Structure of human galactokinase 1 bound with 2-(4-chlorophenyl)-N-(pyrimidin-2-yl)acetamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, E, D | Galactokinase | polymer | 399 | 43103.0 | 4 | UniProt (P51570) Pfam (PF10509) Pfam (PF00288) Pfam (PF08544) In PDB | Homo sapiens (Human) | Galactose kinase |
2 | A, B, E | beta-D-galactopyranose | non-polymer | 180.2 | 3 | Chemie (GAL) | |||
3 | A, B, E | 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one | non-polymer | 350.4 | 3 | Chemie (HFK) | |||
4 | D | ~{N}-(3-ethanoylphenyl)-2,2,2-tris(fluoranyl)ethanamide | non-polymer | 231.2 | 1 | Chemie (SSY) | |||
5 | water | water | 18.0 | 576 | Chemie (HOH) |
Sequence modifications
A, B, E, D: 2 - 392 (UniProt: P51570)
PDB | External Database | Details |
---|---|---|
Met -6 | - | initiating methionine |
Ala -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
Ala 252 | Lys 252 | engineered mutation |
Ala 253 | Glu 253 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 172411.9 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1822.9 | |
All* | Total formula weight | 174234.8 |