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6ZGW

Structure of human galactokinase 1 bound with (4-chlorophenyl)methyl pyridine-3-carboxylate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, E, DGalactokinasepolymer39943103.04UniProt (P51570)
Pfam (PF10509)
Pfam (PF00288)
Pfam (PF08544)
In PDB
Homo sapiens (Human)Galactose kinase
2A, B, Ebeta-D-galactopyranosenon-polymer180.23Chemie (GAL)
3A, B, E2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-onenon-polymer350.43Chemie (HFK)
4D(4-chlorophenyl)methyl pyridine-3-carboxylatenon-polymer247.71Chemie (QKW)
5waterwater18.0480Chemie (HOH)
Sequence modifications
A, B, E, D: 2 - 392 (UniProt: P51570)
PDBExternal DatabaseDetails
Met -6-initiating methionine
Ala -5-expression tag
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
His 0-expression tag
His 1-expression tag
Ala 252Lys 252engineered mutation
Ala 253Glu 253engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight172411.9
Non-Polymers*Number of molecules7
Total formula weight1839.4
All*Total formula weight174251.3
*Water molecules are not included.

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PDB entries from 2024-07-24

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