6ZDL
Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG and hexatungstotellurate(VI) TEW
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | Glycoprotein endo-alpha-1,2-mannosidase | polymer | 382 | 44783.1 | 1 | UniProt (Q5SRI9) Pfam (PF16317) | Homo sapiens (Human) | hEndo,Mandaselin |
| 2 | B (AAA) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) PubChem (23831) | |||
| 3 | C (AAA) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D, E, F (AAA) | 6-tungstotellurate(VI) | non-polymer | 1614.6 | 3 | Chemie (TEW) | |||
| 5 | G (AAA) | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE | non-polymer | 147.2 | 1 | Chemie (IFM) PubChem (25178019) PubChem (44578588) PubChem (447607) PubChem (57181891) PubChem (57590942) PubChem (4452693) PubChem (89062053) PubChem (10240946) PubChem (10510991) PubChem (10820691) PubChem (10844524) PubChem (15235482) PubChem (130784980) PubChem (130905021) PubChem (174012304) | |||
| 6 | H (AAA) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 7 | I (AAA) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
AAA: 98 - 462 (UniProt: Q5SRI9)
| PDB | External Database | Details |
|---|---|---|
| Met 81 | - | initiating methionine |
| Asn 82 | - | expression tag |
| His 83 | - | expression tag |
| Lys 84 | - | expression tag |
| Val 85 | - | expression tag |
| His 86 | - | expression tag |
| His 87 | - | expression tag |
| His 88 | - | expression tag |
| His 89 | - | expression tag |
| His 90 | - | expression tag |
| His 91 | - | expression tag |
| Ile 92 | - | expression tag |
| Glu 93 | - | expression tag |
| Gly 94 | - | expression tag |
| Arg 95 | - | expression tag |
| His 96 | - | expression tag |
| Met 97 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44783.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 5433.8 | |
| All* | Total formula weight | 50216.9 |
