6ZDL
Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with GlcIFG and hexatungstotellurate(VI) TEW
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | Glycoprotein endo-alpha-1,2-mannosidase | polymer | 382 | 44783.1 | 1 | UniProt (Q5SRI9) Pfam (PF16317) | Homo sapiens (Human) | hEndo,Mandaselin |
| 2 | B (AAA) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 3 | C (AAA) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E, F (AAA) | 6-tungstotellurate(VI) | non-polymer | 1614.6 | 3 | Chemie (TEW) | |||
| 5 | G (AAA) | 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE | non-polymer | 147.2 | 1 | Chemie (IFM) | |||
| 6 | H (AAA) | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 7 | I (AAA) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
AAA: 98 - 462 (UniProt: Q5SRI9)
| PDB | External Database | Details |
|---|---|---|
| Met 81 | - | initiating methionine |
| Asn 82 | - | expression tag |
| His 83 | - | expression tag |
| Lys 84 | - | expression tag |
| Val 85 | - | expression tag |
| His 86 | - | expression tag |
| His 87 | - | expression tag |
| His 88 | - | expression tag |
| His 89 | - | expression tag |
| His 90 | - | expression tag |
| His 91 | - | expression tag |
| Ile 92 | - | expression tag |
| Glu 93 | - | expression tag |
| Gly 94 | - | expression tag |
| Arg 95 | - | expression tag |
| His 96 | - | expression tag |
| Met 97 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 44783.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 5433.8 | |
| All* | Total formula weight | 50216.9 |
