6ZDK

Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with HEPES and hexatungstotellurate(VI) TEW

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AAA	Glycoprotein endo-alpha-1,2-mannosidase	polymer	382	44783.1	1	UniProt (Q5SRI9) Pfam (PF16317) In PDB	Homo sapiens (Human)	hEndo,Mandaselin
2	AAA	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
3	AAA	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
4	AAA	6-tungstotellurate(VI)	non-polymer		1614.6	3	Chemie (TEW)
5		water	water		18.0	165	Chemie (HOH)

Sequence modifications

AAA: 98 - 462 (UniProt: Q5SRI9)

PDB	External Database	Details
Met 81	-	initiating methionine
Asn 82	-	expression tag
His 83	-	expression tag
Lys 84	-	expression tag
Val 85	-	expression tag
His 86	-	expression tag
His 87	-	expression tag
His 88	-	expression tag
His 89	-	expression tag
His 90	-	expression tag
His 91	-	expression tag
Ile 92	-	expression tag
Glu 93	-	expression tag
Gly 94	-	expression tag
Arg 95	-	expression tag
His 96	-	expression tag
Met 97	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44783.1
Non-Polymers*	Number of molecules	5
	Total formula weight	5106.5
All*	Total formula weight	49889.6

*Water molecules are not included.