6ZCS
SYK Kinase domain in complex with azabenzimidazole inhibitor 3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein kinase SYK | polymer | 299 | 34881.0 | 1 | UniProt (P43405) Pfam (PF07714) In PDB | Homo sapiens (Human) | Spleen tyrosine kinase,p72-Syk |
2 | A | (3~{R},4~{R})-~{N}4-[1-[2-(1-methylindol-4-yl)-3~{H}-imidazo[4,5-b]pyridin-7-yl]pyrazol-4-yl]oxane-3,4-diamine | non-polymer | 428.5 | 1 | Chemie (QFE) | |||
3 | water | water | 18.0 | 350 | Chemie (HOH) |
Sequence modifications
A: 343 - 635 (UniProt: P43405)
PDB | External Database | Details |
---|---|---|
His 636 | - | expression tag |
His 637 | - | expression tag |
His 638 | - | expression tag |
His 639 | - | expression tag |
His 640 | - | expression tag |
His 641 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 34881.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 428.5 | |
All* | Total formula weight | 35309.5 |