6ZB1

C-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH GSK620

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (AAA)	Bromodomain-containing protein 2	polymer	115	13432.5	1	UniProt (P25440) Pfam (PF00439)	Homo sapiens (Human)	O27.1.1,Really interesting new gene 3 protein
2	B, C (AAA)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
3	D (AAA)	~{N}5-cyclopropyl-~{N}3-methyl-2-oxidanylidene-1-(phenylmethyl)pyridine-3,5-dicarboxamide	non-polymer		325.4	1	Chemie (QCZ)
4	E (AAA)	water	water		18.0	199	Chemie (HOH)

Sequence modifications

AAA: 344 - 455 (UniProt: P25440)

PDB	External Database	Details
Gly 341	-	expression tag
Ser 342	-	expression tag
Met 343	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	13432.5
Non-Polymers*	Number of molecules	3
	Total formula weight	449.5
All*	Total formula weight	13882.0

*Water molecules are not included.