6Z8K

La Crosse virus polymerase at elongation mimicking stage

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, T	La Crosse virus 5' vRNA 1-10	polymer	10	3218.0	2		La Crosse orthobunyavirus
2	X	La Crosse virus 5' vRNA (9-16)	polymer	8	2509.6	1		La Crosse orthobunyavirus
3	H, P	La Crosse virus 3' vRNA (1-16)	polymer	16	5060.0	2		La Crosse orthobunyavirus
4	A	RNA-directed RNA polymerase L	polymer	2285	266047.5	1	UniProt (A5HC98) Pfam (PF15518) Pfam (PF04196) Pfam (PF21561) In PDB	La Crosse orthobunyavirus	Protein L,Large structural protein,Replicase,Transcriptase
5	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
6	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)

Sequence modifications

A: 1 - 2263 (UniProt: A5HC98)

PDB	External Database	Details
Met -21	-	initiating methionine
Gly -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
Asp -13	-	expression tag
Tyr -12	-	expression tag
Asp -11	-	expression tag
Ile -10	-	expression tag
Pro -9	-	expression tag
Thr -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	285113.0
Non-Polymers*	Number of molecules	2
	Total formula weight	89.7
All*	Total formula weight	285202.7

*Water molecules are not included.