6Z7U

Myosin-II motor domain complexed with blebbistatin in a new ADP-release conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Myosin-2 heavy chain	polymer	777	88724.2	1	UniProt (P08799) Pfam (PF02736) Pfam (PF00063)	Dictyostelium discoideum	Myosin II heavy chain
2	B, E, F, G, H... (A)	1,2-ETHANEDIOL	non-polymer		62.1	9	Chemie (EDO)
3	C (A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
4	D (A)	(-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE	non-polymer		292.3	1	Chemie (BIT)
5	M (A)	water	water		18.0	59	Chemie (HOH)

Sequence modifications

A: 2 - 761 (UniProt: P08799)

PDB	External Database	Details
Met -10	-	initiating methionine
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Asp -2	-	expression tag
Gly -1	-	expression tag
Thr 0	-	expression tag
Glu 1	-	expression tag
Leu 762	-	expression tag
Glu 763	-	expression tag
Ser 764	-	expression tag
Asn 765	-	expression tag
Glu 766	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	88724.2
Non-Polymers*	Number of molecules	11
	Total formula weight	1278.1
All*	Total formula weight	90002.3

*Water molecules are not included.