6Z3G
Repulsive Guidance Molecule A (RGMA) in complex with Growth Differentiation Factor 5 (GDF5)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Growth/differentiation factor 5 | polymer | 117 | 13405.5 | 1 | UniProt (P43026) Pfam (PF00019) In PDB | Homo sapiens (Human) | GDF-5,Bone morphogenetic protein 14,BMP-14,Cartilage-derived morphogenetic protein 1,CDMP-1,Lipopolysaccharide-associated protein 4,LPS-associated protein 4,Radotermin |
2 | B | Repulsive guidance molecule A | polymer | 106 | 11628.8 | 1 | UniProt (Q96B86) Pfam (PF06535) In PDB | Homo sapiens (Human) | RGM domain family member A |
3 | A | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) |
Sequence modifications
A: 387 - 501 (UniProt: P43026)
B: 54 - 139 (UniProt: Q96B86)
PDB | External Database | Details |
---|---|---|
Met 385 | - | initiating methionine |
Lys 386 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Glu 43 | - | expression tag |
Thr 44 | - | expression tag |
Gly 45 | - | expression tag |
Ser 46 | - | expression tag |
Pro 47 | - | expression tag |
Cys 48 | - | expression tag |
Lys 49 | - | expression tag |
Ile 50 | - | expression tag |
Leu 51 | - | expression tag |
Lys 52 | - | expression tag |
Cys 53 | - | expression tag |
Gly 140 | - | expression tag |
Thr 141 | - | expression tag |
Lys 142 | - | expression tag |
His 143 | - | expression tag |
His 144 | - | expression tag |
His 145 | - | expression tag |
His 146 | - | expression tag |
His 147 | - | expression tag |
His 148 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 25034.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 192.1 | |
All* | Total formula weight | 25226.4 |