6Z2Z
M2 mutant (R111K:Y134F:T54V:R132Q:P39Y:R59Y) of human cellular retinoic acid binding protein II - 2a conjugate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cellular retinoic acid-binding protein 2 | polymer | 141 | 15992.3 | 1 | UniProt (P29373) Pfam (PF00061) | Homo sapiens (Human) | Cellular retinoic acid-binding protein II,CRABP-II |
| 2 | B (A) | methyl (~{Z})-3-(6-ethynylnaphthalen-2-yl)-2-methyl-prop-2-enoate | non-polymer | 250.3 | 1 | Chemie (Q5W) | |||
| 3 | C (A) | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 0 - 137 (UniProt: P29373)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Tyr 39 | Pro 40 | engineered mutation |
| Val 54 | Thr 55 | engineered mutation |
| Tyr 59 | Arg 60 | engineered mutation |
| Lys 111 | Arg 112 | engineered mutation |
| Gln 132 | Arg 133 | engineered mutation |
| Phe 134 | Tyr 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15992.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 250.3 | |
| All* | Total formula weight | 16242.6 |
