6Z0Q

Crystal structure of SAICAR Synthetase (PurC) from Mycobacterium abscessus in complex with fragment 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Phosphoribosylaminoimidazole-succinocarboxamide synthase	polymer	306	33900.2	1	UniProt (B1MHW4) Pfam (PF01259) In PDB	Mycobacteroides abscessus ATCC 19977	SAICAR synthetase
2	A	ethyl (2~{S},3~{R})-3-(5-bromanylpyridin-2-yl)-2-fluoranyl-3-oxidanyl-propanoate	non-polymer		292.1	1	Chemie (Q4K)
3	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4		water	water		18.0	299	Chemie (HOH)

Sequence modifications

A: 1 - 297 (UniProt: B1MHW4)

PDB	External Database	Details
Met -8	-	initiating methionine
Ser -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33900.2
Non-Polymers*	Number of molecules	2
	Total formula weight	388.2
All*	Total formula weight	34288.3

*Water molecules are not included.