6YYP

Structure of Cathepsin S in complex with Compound 2

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (AAA, BBB)	Cathepsin S	polymer	225	25122.2	2	UniProt (P25774) Pfam (PF00112)	Homo sapiens (Human)
2	C, D, I, J, K... (AAA, BBB)	ACETATE ION	non-polymer		59.0	6	Chemie (ACT)
3	E (AAA)	1-(furan-2-ylmethyl)-5-(trifluoromethyl)benzimidazol-2-amine	non-polymer		281.2	1	Chemie (Q1H)
4	F (BBB)	SUCCINIC ACID	non-polymer		118.1	1	Chemie (SIN)
5	G, H (BBB)	MALONIC ACID	non-polymer		104.1	2	Chemie (MLA)
6	M, N (AAA, BBB)	water	water		18.0	444	Chemie (HOH)

Sequence modifications

AAA, BBB: -1 - 217 (UniProt: P25774)

PDB	External Database	Details
His 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
His 221	-	expression tag
His 222	-	expression tag
His 223	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50244.3
Non-Polymers*	Number of molecules	10
	Total formula weight	961.7
All*	Total formula weight	51206.1

*Water molecules are not included.