6YYE
TREM2 extracellular domain (19-131) in complex with single-chain variable fragment (scFv-2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Triggering receptor expressed on myeloid cells 2 | polymer | 116 | 12951.6 | 2 | UniProt (Q9NZC2) Pfam (PF07686) | Homo sapiens (Human) | TREM-2,Triggering receptor expressed on monocytes 2 |
| 2 | C, D (C, D) | TREM2 Single chain variable 2 | polymer | 247 | 26200.9 | 2 | Homo sapiens (Human) | ||
| 3 | E (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
A, B: 19 - 131 (UniProt: Q9NZC2)
| PDB | External Database | Details |
|---|---|---|
| Glu 16 | - | expression tag |
| Thr 17 | - | expression tag |
| Gly 18 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 78305.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 78526.2 |
