6YXT

Crystal structure of the ADP-bound form of choline kinase from Plasmodium falciparum

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Choline kinase	polymer	382	45334.5	1	UniProt (Q8IM71) Pfam (PF01633) In PDB	Plasmodium falciparum (isolate 3D7)
2	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
5		water	water		18.0	96	Chemie (HOH)

Sequence modifications

A: 79 - 440 (UniProt: Q8IM71)

PDB	External Database	Details
Met 59	-	initiating methionine
Gly 60	-	expression tag
Ser 61	-	expression tag
Ser 62	-	expression tag
His 63	-	expression tag
His 64	-	expression tag
His 65	-	expression tag
His 66	-	expression tag
His 67	-	expression tag
His 68	-	expression tag
Ser 69	-	expression tag
Ser 70	-	expression tag
Gly 71	-	expression tag
Glu 72	-	expression tag
Asn 73	-	expression tag
Leu 74	-	expression tag
Tyr 75	-	expression tag
Phe 76	-	expression tag
Gln 77	-	expression tag
Gly 78	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45334.5
Non-Polymers*	Number of molecules	6
	Total formula weight	662.0
All*	Total formula weight	45996.5

*Water molecules are not included.