6YVI
EED in complex with a cyano-benzofuran
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Polycomb protein EED | polymer | 366 | 42299.2 | 2 | UniProt (O75530) Pfam (PF00400) In PDB | Homo sapiens (Human) | hEED,Embryonic ectoderm development protein,WD protein associating with integrin cytoplasmic tails 1,WAIT-1 |
2 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
3 | A | N-(2,3-dihydro-1-benzofuran-4-ylmethyl)-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine | non-polymer | 421.5 | 1 | Chemie (L9W) | |||
4 | B | 5-fluoranyl-4-[[[8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-yl]amino]methyl]-2,3-dihydro-1-benzofuran-7-carbonitrile | non-polymer | 401.4 | 1 | Chemie (PV5) | |||
5 | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 84598.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 862.9 | |
All* | Total formula weight | 85461.3 |