6YUR
Crystal structure of S. aureus FabI inhibited by SKTS1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Enoyl-[acyl-carrier-protein] reductase [NADPH] | polymer | 282 | 31144.2 | 8 | UniProt (A0A0J9X1X7) Pfam (PF13561) UniProt (by SIFTS) (Q2FZQ3) | Staphylococcus aureus | ENR |
| 2 | I, K, M, O, Q... (A, B, C, D, E...) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 8 | Chemie (NAP) | |||
| 3 | J, L, N, P, R... (A, B, C, D, E...) | 6-[4-(4-hexyl-2-oxidanyl-phenoxy)phenoxy]pyridin-2-ol | non-polymer | 379.4 | 8 | Chemie (F9T) | |||
| 4 | AA, BA, CA, DA, EA... (C, D, E, F, G...) | water | water | 18.0 | 806 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: -16 - 256 (UniProt: A0A0J9X1X7)
| PDB | External Database | Details |
|---|---|---|
| Met -25 | - | initiating methionine |
| Lys -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| Pro -17 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 249153.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 8982.8 | |
| All* | Total formula weight | 258136.8 |
