6YR7
14-3-3 sigma in complex with hDMX-342+367 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 14-3-3 protein sigma | polymer | 236 | 26542.9 | 2 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | Q, C | Protein Mdm4 | polymer | 40 | 4529.8 | 2 | UniProt (O15151) In PDB | Homo sapiens | Double minute 4 protein,Mdm2-like p53-binding protein,Protein Mdmx,p53-binding protein Mdm4 |
| 3 | A | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 4 | water | water | 18.0 | 179 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62145.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 282.3 | |
| All* | Total formula weight | 62427.9 |
