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6YOX

14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-027

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer25328226.51UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(P)
p65pS45polymer131412.41UniProt (by SIFTS) (Q04206)Homo sapiens
3C
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4D
(A)
N-[4-(hydroxymethyl)phenyl]acetamidenon-polymer165.21Chemie (L3V)
5E
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
6F
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7G, H
(A, P)
waterwater18.0230Chemie (HOH)
Sequence modifications
A: 1 - 248 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight29638.9
Non-Polymers*Number of molecules4
Total formula weight265.0
All*Total formula weight29904.0
*Water molecules are not included.

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PDB entries from 2024-11-06

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