6YOW
14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26558.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
2 | B (P) | p65pS45 | polymer | 13 | 1412.4 | 1 | UniProt (by SIFTS) (Q04206) | Homo sapiens | |
3 | C (A) | 4-(methylsulfonyl)benzaldehyde | non-polymer | 184.2 | 1 | Chemie (L3Y) | |||
4 | D, E (A, P) | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27971.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 184.2 | |
All* | Total formula weight | 28155.6 |