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6YOW

14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23626558.91UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(P)
p65pS45polymer131412.41UniProt (by SIFTS) (Q04206)Homo sapiens
3C
(A)
4-(methylsulfonyl)benzaldehydenon-polymer184.21Chemie (L3Y)
4D, E
(A, P)
waterwater18.0359Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27971.3
Non-Polymers*Number of molecules1
Total formula weight184.2
All*Total formula weight28155.6
*Water molecules are not included.

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PDB entries from 2024-11-06

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