6YOV
OCT4-SOX2-bound nucleosome - SHL+6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histone H3.1 | polymer | 139 | 15719.4 | 1 | UniProt (P68431) Pfam (PF00125) In PDB | Homo sapiens (Human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 2 | B | Histone H4 | polymer | 105 | 11547.5 | 1 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (Human) | |
| 3 | C, G | Histone H2A type 1-B/E | polymer | 133 | 14447.8 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) In PDB | Homo sapiens (Human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 4 | D, H | Histone H2B type 1-J | polymer | 128 | 14088.3 | 2 | UniProt (P06899) Pfam (PF00125) In PDB | Homo sapiens (Human) | Histone H2B.1,Histone H2B.r,H2B/r |
| 5 | E | Histone H3.1 | polymer | 137 | 15491.2 | 1 | UniProt (P68431) Pfam (PF00125) In PDB | Homo sapiens (Human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 6 | F | Histone H4 | polymer | 106 | 11676.7 | 1 | UniProt (P62805) Pfam (PF15511) In PDB | Homo sapiens (Human) | |
| 7 | I, J | DNA (142-MER) | polymer | 300 | 92645.9 | 2 | synthetic construct | ||
| 8 | K | Green fluorescent protein,POU domain, class 5, transcription factor 1 | polymer | 631 | 69137.8 | 1 | UniProt (P42212) UniProt (Q01860) Pfam (PF00046) Pfam (PF01353) Pfam (PF00157) In PDB | Aequorea victoria (Jellyfish) | Octamer-binding protein 3,Oct-3,Octamer-binding protein 4,Oct-4,Octamer-binding transcription factor 3,OTF-3 |
| 9 | L | Transcription factor SOX-2 | polymer | 105 | 12718.7 | 1 | UniProt (P48431) Pfam (PF00505) In PDB | Homo sapiens (Human) | |
| 10 | A, B, C, D, F... | PENTANEDIAL | non-polymer | 100.1 | 8 | Chemie (PTD) |
Sequence modifications
A: 1 - 136 (UniProt: P68431)
B: 2 - 103 (UniProt: P62805)
C, G: 1 - 130 (UniProt: P04908)
D, H: 1 - 125 (UniProt: P06899)
E: 1 - 134 (UniProt: P68431)
F: 1 - 103 (UniProt: P62805)
K: -248 - -10 (UniProt: P42212)
K: 1 - 360 (UniProt: Q01860)
L: 37 - 118 (UniProt: P48431)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| His 1 | - | expression tag |
| - | Lys 21 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -270 | - | initiating methionine |
| Asp -269 | - | expression tag |
| Trp -268 | - | expression tag |
| Ser -267 | - | expression tag |
| His -266 | - | expression tag |
| Pro -265 | - | expression tag |
| Gln -264 | - | expression tag |
| Phe -263 | - | expression tag |
| Glu -262 | - | expression tag |
| Lys -261 | - | expression tag |
| Ser -260 | - | expression tag |
| Ala -259 | - | expression tag |
| Val -258 | - | expression tag |
| Asp -257 | - | expression tag |
| Glu -256 | - | expression tag |
| Asn -255 | - | expression tag |
| Leu -254 | - | expression tag |
| Tyr -253 | - | expression tag |
| Phe -252 | - | expression tag |
| Gln -251 | - | expression tag |
| Gly -250 | - | expression tag |
| Gly -249 | - | expression tag |
| Val -247 | - | insertion |
| Leu -184 | Phe 64 | conflict |
| Thr -183 | Ser 65 | conflict |
| Lys -42 | Ala 206 | conflict |
| Leu -17 | His 231 | conflict |
| Glu -9 | - | linker |
| Ala -8 | - | linker |
| Ala -7 | - | linker |
| Ala -6 | - | linker |
| Lys -5 | - | linker |
| Glu -4 | - | linker |
| Ala -3 | - | linker |
| Ala -2 | - | linker |
| Ala -1 | - | linker |
| Lys 0 | - | linker |
L: 37 - 118 (UniProt: P48431)
| PDB | External Database | Details |
|---|---|---|
| Met 14 | - | initiating methionine |
| Asp 15 | - | expression tag |
| Trp 16 | - | expression tag |
| Ser 17 | - | expression tag |
| His 18 | - | expression tag |
| Pro 19 | - | expression tag |
| Gln 20 | - | expression tag |
| Phe 21 | - | expression tag |
| Glu 22 | - | expression tag |
| Lys 23 | - | expression tag |
| Ser 24 | - | expression tag |
| Ala 25 | - | expression tag |
| Val 26 | - | expression tag |
| Asp 27 | - | expression tag |
| Glu 28 | - | expression tag |
| Asn 29 | - | expression tag |
| Leu 30 | - | expression tag |
| Tyr 31 | - | expression tag |
| Phe 32 | - | expression tag |
| Gln 33 | - | expression tag |
| Gly 34 | - | expression tag |
| Gly 35 | - | expression tag |
| Met 36 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 378655.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 800.9 | |
| All* | Total formula weight | 379456.3 |
