6YOK
Para-Carborane di-propyl-sulfonamide in complex with CA IX mimic
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29200.9 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | C (A) | Para-Carborane di-propyl-sulfonamide | non-polymer | 376.5 | 1 | Chemie (P82) | |||
4 | D (A) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A: 1 - 260 (UniProt: P00918)
PDB | External Database | Details |
---|---|---|
Ser 65 | Ala 65 | engineered mutation |
Gln 67 | Asn 67 | engineered mutation |
Thr 69 | Glu 69 | engineered mutation |
Leu 91 | Ile 91 | engineered mutation |
Val 130 | Phe 130 | engineered mutation |
Glu 169 | Lys 169 | engineered mutation |
Ala 203 | Leu 203 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29200.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 441.9 | |
All* | Total formula weight | 29642.8 |