6YIQ
tRNA-Guanine Transglycosylase (TGT) in co-crystallized complex (P2) with 6-amino-2-(methylamino)-4-phenethyl-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Queuine tRNA-ribosyltransferase | polymer | 388 | 43069.8 | 2 | UniProt (P28720) Pfam (PF01702) | Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 | Guanine insertion enzyme,tRNA-guanine transglycosylase |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G, H (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | E, I (A, B) | 6-amino-2-(methylamino)-4-phenethyl-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one | non-polymer | 334.4 | 2 | Chemie (OQN) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 538 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 386 (UniProt: P28720)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Lys 312 | Thr 312 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 86139.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1075.8 | |
| All* | Total formula weight | 87215.5 |
