6YIM
Crystal structure of the CREBBP bromodomain in complex with a benzo-diazepine ligand
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | CREBBP | polymer | 119 | 14223.3 | 1 | UniProt (Q92793) Pfam (PF00439) In PDB | Homo sapiens (Human) | |
2 | A | (4~{R})-~{N}-[3-(7-methoxy-3,4-dihydro-2~{H}-quinolin-1-yl)propyl]-4-methyl-2-oxidanylidene-1,3,4,5-tetrahydro-1,5-benzodiazepine-6-carboxamide | non-polymer | 422.5 | 1 | Chemie (OS8) | |||
3 | water | water | 18.0 | 163 | Chemie (HOH) |
Sequence modifications
A: 1081 - 1197 (UniProt: Q92793)
PDB | External Database | Details |
---|---|---|
Ser 1079 | - | expression tag |
Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 14223.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 422.5 | |
All* | Total formula weight | 14645.9 |