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6YIC

14-3-3 sigma in complex with SMAD4 pS403 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23626542.91UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(P)
SMAD4polymer101194.31UniProt (by SIFTS) (Q13485)Homo sapiens
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D, H
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
5E, G
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6F
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
7I, J
(A, P)
waterwater18.0324Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27737.2
Non-Polymers*Number of molecules6
Total formula weight226.8
All*Total formula weight27963.9
*Water molecules are not included.

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PDB entries from 2025-06-11

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