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6YIB

14-3-3 sigma in complex with SMAD3 pS423 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23626542.91UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(P)
SMAD3polymer111228.31UniProt (by SIFTS) (P84022)Homo sapiens
3C, D, E
(A)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
4F, G, H
(A)
CHLORIDE IONnon-polymer35.53Chemie (CL)
5I
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
6J
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
7K
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
8L, M
(A, P)
waterwater18.0314Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27771.2
Non-Polymers*Number of molecules9
Total formula weight334.4
All*Total formula weight28105.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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