6YG5
Crystal structure of MKK7 (MAP2K7) in complex with ASC69
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dual specificity mitogen-activated protein kinase kinase 7 | polymer | 307 | 34976.6 | 1 | UniProt (O14733) Pfam (PF00069) In PDB | Homo sapiens (Human) | MAPKK 7,JNK-activating kinase 2,MAPK/ERK kinase 7,MEK 7,Stress-activated protein kinase kinase 4,SAPKK4,c-Jun N-terminal kinase kinase 2,JNKK 2 |
| 2 | A | [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile | non-polymer | 381.4 | 1 | Chemie (IHH) | |||
| 3 | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 116 - 421 (UniProt: O14733)
| PDB | External Database | Details |
|---|---|---|
| Ser 115 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34976.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 381.4 | |
| All* | Total formula weight | 35358.1 |
