6YBQ
Engineered glycolyl-CoA carboxylase (quintuple mutant) with bound CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Propionyl-CoA carboxylase beta chain | polymer | 510 | 55963.9 | 6 | UniProt (C5AP75) Pfam (PF01039) In PDB | Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) | |
| 2 | G, H, I, J, K... | Propionyl-CoA carboxylase alpha subunit | polymer | 667 | 71987.0 | 6 | UniProt (C5AWU5) Pfam (PF00289) Pfam (PF02786) Pfam (PF02785) Pfam (PF18140) Pfam (PF00364) In PDB | Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1) | |
| 3 | A, B, C, D, E... | COENZYME A | non-polymer | 767.5 | 6 | Chemie (COA) | |||
| 4 | G, H, I, J, K... | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL | non-polymer | 228.3 | 6 | Chemie (BTI) | |||
| 5 | water | water | 18.0 | 871 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 510 (UniProt: C5AP75)
| PDB | External Database | Details |
|---|---|---|
| Ser 100 | Leu 100 | engineered mutation |
| His 143 | Tyr 143 | engineered mutation |
| Ile 407 | Asp 407 | engineered mutation |
| Val 450 | Ile 450 | engineered mutation |
| Arg 502 | Trp 502 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 767705.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5975.1 | |
| All* | Total formula weight | 773680.4 |
