6YAT
Crystal structure of STK4 (MST1) in complex with compound 6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase 4 | polymer | 314 | 35811.9 | 2 | UniProt (Q13043) Pfam (PF00069) | Homo sapiens (Human) | Mammalian STE20-like protein kinase 1,MST-1,STE20-like kinase MST1,Serine/threonine-protein kinase Krs-2 |
| 2 | C (A) | (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid | non-polymer | 237.3 | 1 | Chemie (3FX) | |||
| 3 | D, E, F, G, H... (A) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 4 | K, L (A, B) | 4-[5-(3-chlorophenyl)-7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl]morpholine | non-polymer | 314.8 | 2 | Chemie (OJ5) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 44 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 311 (UniProt: Q13043)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Glu 312 | - | expression tag |
| Gly 313 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71623.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1511.5 | |
| All* | Total formula weight | 73135.3 |
