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6YAM

Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(1)
initiator methionylated tRNApolymer7524376.61Oryctolagus cuniculus (Rabbit)
2B
(l)
60s ribosomal protein l41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)
Oryctolagus cuniculus (Rabbit)eL41
3C
(C)
40S ribosomal protein uS2polymer20823360.81UniProt (G1TLT8)
Pfam (PF00318)
Oryctolagus cuniculus (Rabbit)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
4D
(D)
40S ribosomal protein eS1polymer26429929.01UniProt (G1TN72)
Pfam (PF01015)
Oryctolagus cuniculus (Rabbit)
5E
(E)
40S ribosomal protein uS5polymer22624814.31Oryctolagus cuniculus (Rabbit)
6F
(F)
40S ribosomal protein uS3polymer22725158.51UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)
Oryctolagus cuniculus (Rabbit)
7G
(G)
40S ribosomal protein eS4polymer26329658.91UniProt (G1TK17)
Pfam (PF00467)
Pfam (PF16121)
Pfam (PF08071)
Pfam (PF00900)
Oryctolagus cuniculus (Rabbit)
8H
(H)
40S ribosomal protein uS7polymer19121525.91UniProt (U3KMN4)
Pfam (PF00177)
Oryctolagus cuniculus (Rabbit)
9I
(I)
40S ribosomal protein eS6polymer23727471.51UniProt (G1TM55)
Pfam (PF01092)
Oryctolagus cuniculus (Rabbit)
10J
(J)
ribosomal protein eS7polymer19021716.41UniProt (G1SVB0)Oryctolagus cuniculus (Rabbit)
11K
(K)
40S ribosomal protein eS8polymer20623902.91UniProt (G1TJW1)
Pfam (PF01201)
Oryctolagus cuniculus (Rabbit)
12L
(L)
40S ribosomal protein uS4polymer18221266.21UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)
Oryctolagus cuniculus (Rabbit)
13M
(M)
40S ribosomal protein eS10polymer9811774.01UniProt (G1T168)
Pfam (PF03501)
Oryctolagus cuniculus (Rabbit)
14N
(N)
40S ribosomal protein uS17polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)
Oryctolagus cuniculus (Rabbit)
15O
(O)
40S ribosomal protein eS12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)
Oryctolagus cuniculus (Rabbit)
16P
(P)
ribosomal protein uS15polymer15017128.21UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)
Oryctolagus cuniculus (Rabbit)
17Q
(Q)
40S ribosomal protein uS11polymer15116302.81UniProt (G1T1F0)
Pfam (PF00411)
Oryctolagus cuniculus (Rabbit)
18R
(S)
40S ribosomal protein uS9polymer14115975.81UniProt (G1SGX4)
Pfam (PF00380)
Oryctolagus cuniculus (Rabbit)
19S
(T)
40S ribosomal protein eS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)
Oryctolagus cuniculus (Rabbit)
20T
(V)
40S ribosomal protein eS19polymer14516235.81UniProt (G1TN62)
Pfam (PF01090)
Oryctolagus cuniculus (Rabbit)
21U
(W)
40S ribosomal protein uS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)
Oryctolagus cuniculus (Rabbit)
22V
(X)
40S ribosomal protein eS21polymer828896.11UniProt (G1TM82)
Pfam (PF01249)
Oryctolagus cuniculus (Rabbit)
23W
(Y)
40S ribosomal protein uS8polymer13014865.61UniProt (G1TG89)
Pfam (PF00410)
Oryctolagus cuniculus (Rabbit)
24X
(Z)
40S ribosomal protein uS12polymer14215757.61UniProt (G1SZ47)
Pfam (PF00164)
Oryctolagus cuniculus (Rabbit)
25Y
(a)
40S ribosomal protein eS24polymer13315434.31UniProt (G1TS40)
Pfam (PF01282)
Oryctolagus cuniculus (Rabbit)
26Z
(b)
40S ribosomal protein eS26polymer11512961.51UniProt (G1TFE8)
Pfam (PF01283)
Oryctolagus cuniculus (Rabbit)
27AA
(c)
40S ribosomal protein eS27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)
Oryctolagus cuniculus (Rabbit)
28BA
(d)
40S ribosomal protein eS28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)
Oryctolagus cuniculus (Rabbit)
29CA
(e)
ribosomal protein uS14polymer536364.41UniProt (G1U7M4)
Pfam (PF00253)
Oryctolagus cuniculus (Rabbit)
30DA
(f)
ribosomal protein eS31polymer718358.91UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)
Oryctolagus cuniculus (Rabbit)
31EA
(g)
ribosomal protein RACK1polymer31334669.11UniProt (G1SJB4)
Pfam (PF00400)
Oryctolagus cuniculus (Rabbit)
32FA
(n)
ribosomal protein eS25polymer758526.11UniProt (G1TDB3)
Pfam (PF03297)
Oryctolagus cuniculus (Rabbit)
33GA
(i)
40S ribosomal protein eS30polymer596741.01UniProt (G1T8A2)
Pfam (PF04758)
Oryctolagus cuniculus (Rabbit)
34HA
(2)
18S ribosomal RNApolymer1863601015.71Oryctolagus cuniculus (Rabbit)
35IA
(A)
eukaryotic translation initiation factor 2 subunit alphapolymer26630633.31UniProt (G1T2G4)
Pfam (PF00575)
Pfam (PF07541)
Oryctolagus cuniculus (Rabbit)
36JA
(B)
eukaryotic translation initiation factor 2 subunit gammapolymer42245862.41Oryctolagus cuniculus (Rabbit)
37KA
(j)
eukaryotic translation initiation factor 1Apolymer14416488.41Oryctolagus cuniculus (Rabbit)
38LA
(k)
ATP-binding cassette sub-family E member 1 (ABCE1)polymer59566986.81Oryctolagus cuniculus (Rabbit)
39MA
(U)
40S ribosomal protein uS13polymer15217759.81UniProt (G1TPG3)
Pfam (PF00416)
Oryctolagus cuniculus (Rabbit)
40NA
(R)
40S ribosomal protein uS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)
Oryctolagus cuniculus (Rabbit)
41OA
(3)
beta-globin mRNApolymer4514454.71Homo sapiens
42PA
(m)
eukaryotic translation initiation factor 3 subunit dpolymer54864042.71Oryctolagus cuniculus (Rabbit)
43QA
(y)
Eukaryotic translation initiation factor 3 subunit Apolymer1350163226.91UniProt (A0A5F9C991)
Pfam (PF22591)
Pfam (PF01399)
Oryctolagus cuniculus (Rabbit)eIF3a,Eukaryotic translation initiation factor 3 subunit 10,eIF-3-theta
44RA
(v)
Eukaryotic translation initiation factor 3 subunit Cpolymer913105676.21UniProt (G1U971)
Pfam (PF05470)
Pfam (PF01399)
Oryctolagus cuniculus (Rabbit)eIF3c,Eukaryotic translation initiation factor 3 subunit 8,eIF3 p110
45SA
(w)
Eukaryotic translation initiation factor 3 subunit Epolymer44552281.61UniProt (G1SUC8)
Pfam (PF09440)
Pfam (PF01399)
Pfam (PF21357)
Oryctolagus cuniculus (Rabbit)eIF3e,Eukaryotic translation initiation factor 3 subunit 6,eIF-3 p48
46TA
(q)
Eukaryotic translation initiation factor 3 subunit Fpolymer27230111.31UniProt (G1SLC2)
Pfam (PF01398)
Pfam (PF13012)
Oryctolagus cuniculus (Rabbit)eIF3f,Eukaryotic translation initiation factor 3 subunit 5,eIF-3-epsilon,eIF3 p47
47UA
(r)
eukaryotic translation initiation factor 3 subunit hpolymer35239954.31Oryctolagus cuniculus (Rabbit)
48VA
(s)
Eukaryotic translation initiation factor 3 subunit Kpolymer21825129.71UniProt (G1T3L2)
Pfam (PF10075)
Oryctolagus cuniculus (Rabbit)eIF3k,Eukaryotic translation initiation factor 3 subunit 12,eIF-3 p25
49WA
(t)
eukaryotic translation initiation factor 3 subunit lpolymer56466776.71Oryctolagus cuniculus (Rabbit)
50XA
(u)
Eukaryotic translation initiation factor 3 subunit Mpolymer37442555.81UniProt (G1SLW8)
Pfam (PF01399)
Pfam (PF18005)
Oryctolagus cuniculus (Rabbit)eIF3m
51YA, ZA
(k)
IRON/SULFUR CLUSTERnon-polymer351.62Chemie (SF4)
52AB
(k)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
53BB, CB
(k)
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTERnon-polymer522.22Chemie (GNP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains50
Total formula weight1965945.0
Non-Polymers*Number of molecules5
Total formula weight1772.0
All*Total formula weight1967717.0
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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