6Y9R
Crystal structure of GSK-3b in complex with the 1H-indazole-3-carboxamide inhibitor 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glycogen synthase kinase-3 beta | polymer | 350 | 39882.8 | 1 | UniProt (P49841) Pfam (PF00069) | Homo sapiens (Human) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
| 2 | B (A) | ~{N}-[[1-(2-methoxyethyl)piperidin-4-yl]methyl]-5-(5-propan-2-yloxypyridin-3-yl)-1~{H}-indazole-3-carboxamide | non-polymer | 451.6 | 1 | Chemie (OH8) | |||
| 3 | C (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F (A) | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39882.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 694.8 | |
| All* | Total formula weight | 40577.6 |
