6Y81
Fragment KCL_1088 in complex with MAP kinase p38-alpha
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 14 | polymer | 360 | 41322.1 | 1 | UniProt (P47811) Pfam (PF00069) | Mus musculus (House mouse) | MAPK 14,CRK1,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha |
| 2 | B (A) | 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE | non-polymer | 338.4 | 1 | Chemie (SB4) | |||
| 3 | C, D, E, F, G... (A) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | I, J (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | K (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | M (A) | (3~{R})-~{N}-[(2-azanyl-2-adamantyl)methyl]-3-[[6-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]pyridin-3-yl]sulfonylamino]-3-phenyl-propanamide | non-polymer | 565.7 | 1 | Chemie (OG5) | |||
| 8 | N (A) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A: 1 - 360 (UniProt: P47811)
| PDB | External Database | Details |
|---|---|---|
| Ser 162 | Cys 162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41322.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1355.6 | |
| All* | Total formula weight | 42677.7 |
