6Y7W
Fragment KCL_1337 in complex with MAP kinase p38-alpha
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mitogen-activated protein kinase 14 | polymer | 360 | 41322.1 | 1 | UniProt (P47811) Pfam (PF00069) In PDB | Mus musculus (House mouse) | MAPK 14,CRK1,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha |
| 2 | A | 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE | non-polymer | 338.4 | 1 | Chemie (SB4) | |||
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | A | (2~{R})-~{N}-[(2-azanyl-2-adamantyl)methyl]-4-[6-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]pyridin-3-yl]sulfonyl-2-methyl-morpholine-2-carboxamide | non-polymer | 545.7 | 1 | Chemie (OFW) | |||
| 6 | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 1 - 360 (UniProt: P47811)
| PDB | External Database | Details |
|---|---|---|
| Ser 162 | Cys 162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41322.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1079.8 | |
| All* | Total formula weight | 42401.9 |
