6Y76
AP01 - a redesigned transferrin receptor apical domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transferrin receptor protein 1 | polymer | 168 | 18052.5 | 2 | UniProt (P02786) Pfam (PF02225) | Homo sapiens (Human) | Trfr,T9,p90 |
| 2 | C, D, E (A, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 3 | F, G (A, B) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 156 (UniProt: P02786)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ser 24 | Tyr 219 | engineered mutation |
| Asn 27 | Tyr 222 | engineered mutation |
| Thr 103 | Phe 298 | engineered mutation |
| - | His 300 | deletion |
| - | Ala 301 | deletion |
| - | His 302 | deletion |
| - | Leu 303 | deletion |
| - | Gly 304 | deletion |
| - | Thr 305 | deletion |
| - | Gly 306 | deletion |
| - | Asp 307 | deletion |
| - | Pro 308 | deletion |
| - | Tyr 309 | deletion |
| - | Thr 310 | deletion |
| - | Pro 311 | deletion |
| - | Gly 312 | deletion |
| - | Phe 313 | deletion |
| - | Pro 314 | deletion |
| - | Ser 315 | deletion |
| - | Phe 316 | deletion |
| - | Asn 317 | deletion |
| - | His 318 | deletion |
| - | Thr 319 | deletion |
| - | Gln 320 | deletion |
| - | Phe 321 | deletion |
| - | Pro 322 | deletion |
| - | Pro 323 | deletion |
| - | Ser 324 | deletion |
| - | Arg 325 | deletion |
| - | Ser 326 | deletion |
| Lys 105 | Ser 327 | engineered mutation |
| Lys 107 | Leu 329 | engineered mutation |
| Ser 108 | Pro 330 | engineered mutation |
| Gly 109 | Asn 331 | engineered mutation |
| Gly 157 | - | expression tag |
| Ser 158 | - | expression tag |
| Gly 159 | - | expression tag |
| Ser 160 | - | expression tag |
| Leu 161 | - | expression tag |
| Glu 162 | - | expression tag |
| His 163 | - | expression tag |
| His 164 | - | expression tag |
| His 165 | - | expression tag |
| His 166 | - | expression tag |
| His 167 | - | expression tag |
| His 168 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36105.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 69.0 | |
| All* | Total formula weight | 36174.0 |
