6Y3W
Ternary complex of 14-3-3 sigma (C38N), Estrogen Related Receptor gamma (DBD) phosphopeptide, and disulfide PPI stabilizer 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26553.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (B) | Estrogen Related Receptor gamma phosphopetide | polymer | 10 | 1215.4 | 1 | UniProt (by SIFTS) (P62508) | Homo sapiens | |
| 3 | C, E, F (A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | G (A) | 3-fluoranyl-~{N}-methyl-~{N}-(2-sulfanylethyl)benzamide | non-polymer | 213.3 | 1 | Chemie (O85) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 366 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asn 38 | Cys 38 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27769.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 321.6 | |
| All* | Total formula weight | 28090.9 |
