6Y2V
Crystal structure of the double mutant L13R I16K of Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Low molecular weight phosphotyrosine protein phosphatase | polymer | 158 | 18061.5 | 1 | UniProt (P24666) Pfam (PF01451) | Homo sapiens (Human) | LMW-PTPase,Adipocyte acid phosphatase,Low molecular weight cytosolic acid phosphatase,Red cell acid phosphatase 1 |
| 2 | B (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D (A) | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A: 0 - 157 (UniProt: P24666)
| PDB | External Database | Details |
|---|---|---|
| Arg 13 | Leu 14 | engineered mutation |
| Lys 16 | Ile 17 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18061.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 245.1 | |
| All* | Total formula weight | 18306.6 |
