6Y17

Crystal structure of an NCoR1BBD2-BCL6BTB chimera in complex with nebulinSH3-NCoR1BBD1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Nuclear receptor corepressor 1,B-cell lymphoma 6 protein	polymer	137	15603.0	2	UniProt (O75376) UniProt (P41182) Pfam (PF00651)	Homo sapiens (Human)	N-CoR1,BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51
2	C, D (C, D)	Nebulin,Nuclear receptor corepressor 1	polymer	82	8864.0	2	UniProt (H0Y786) UniProt (O75376) UniProt (by SIFTS) (P20929)	Homo sapiens (Human)	N-CoR1
3	E (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
4	F, G, H, I (A, B, C, D)	water	water		18.0	362	Chemie (HOH)

Sequence modifications

A, B: -5 - 3 (UniProt: O75376)

PDB	External Database	Details
Gly -7	-	expression tag
Pro -6	-	expression tag
Gly 4	-	linker
Gly 5	-	linker

A, B: 6 - 129 (UniProt: P41182)

PDB	External Database	Details
Gln 8	Cys 8	conflict
Arg 67	Cys 67	conflict
Asn 84	Cys 84	conflict

C, D: 1 - 60 (UniProt: H0Y786)

PDB	External Database	Details
Gly -1	-	expression tag
Pro 0	-	expression tag
Gly 61	-	linker
Gly 62	-	linker
Gly 63	-	linker

C, D: 64 - 80 (UniProt: O75376)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	48934.0
Non-Polymers*	Number of molecules	1
	Total formula weight	23.0
All*	Total formula weight	48957.0

*Water molecules are not included.