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6Y08

Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Thymidylate synthasepolymer30735001.02UniProt (P07607)
Pfam (PF00303)
Mus musculus (House mouse)TSase
2C, E
(A, B)
2'-DEOXYURIDINE 5'-MONOPHOSPHATEnon-polymer308.22Chemie (UMP)
3D, F
(A, B)
Sulfamethoxazolenon-polymer253.32Chemie (08D)
4G, H
(A, B)
waterwater18.060Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight70002.0
Non-Polymers*Number of molecules4
Total formula weight1122.9
All*Total formula weight71125.0
*Water molecules are not included.

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PDB entries from 2025-06-25

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