6XXS

Crystal structure of an NCoR1BBD2-BCL6BTB chimera in complex with the NcoR1 BBD1 corepressor peptide.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, G (A, B, F)	B-cell lymphoma 6 protein	polymer	135	15488.9	3	UniProt (P41182) Pfam (PF00651)	Homo sapiens (Human)	BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51
2	C, D, F, H (C, D, G, H)	Nuclear receptor corepressor 1	polymer	17	1942.3	4	UniProt (O75376)	Homo sapiens	N-CoR1
3	E (E)	B-cell lymphoma 6 protein	polymer	126	14498.8	1	UniProt (P41182) Pfam (PF00651)	Homo sapiens (Human)	BCL-6,B-cell lymphoma 5 protein,BCL-5,Protein LAZ-3,Zinc finger and BTB domain-containing protein 27,Zinc finger protein 51

Sequence modifications

A, B, F: 6 - 129 (UniProt: P41182)

PDB	External Database	Details
Gly -5	-	expression tag
Pro -4	-	expression tag
Ser -3	-	expression tag
Ser -2	-	expression tag
Asp -1	-	expression tag
Leu 0	-	expression tag
Tyr 1	-	expression tag
Leu 2	-	expression tag
Arg 3	-	expression tag
Pro 4	-	expression tag
Gly 5	-	expression tag
Gln 8	Cys 8	engineered mutation
Arg 67	Cys 67	engineered mutation
Asn 84	Cys 84	engineered mutation

E: 6 - 129 (UniProt: P41182)

PDB	External Database	Details
Gly 4	-	expression tag
Pro 5	-	expression tag
Gln 8	Cys 8	engineered mutation
Arg 67	Cys 67	engineered mutation
Asn 84	Cys 84	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	68734.6
All*	Total formula weight	68734.6

*Water molecules are not included.