6XWM
Mechanism of substrate release in neurotransmitter:sodium symporters: the structure of LeuT in an inward-facing occluded conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Na(+):neurotransmitter symporter (Snf family) | polymer | 519 | 57962.3 | 2 | UniProt (O67854) Pfam (PF00209) | Aquifex aeolicus VF5 | |
| 2 | C, F (A, B) | PHENYLALANINE | non-polymer | 165.2 | 2 | Chemie (PHE) | |||
| 3 | D, E, G, H (A, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 4 | I, J (A, B) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 513 (UniProt: O67854)
| PDB | External Database | Details |
|---|---|---|
| Ala 8 | Trp 8 | conflict |
| Gly 514 | - | expression tag |
| Thr 515 | - | expression tag |
| Leu 516 | - | expression tag |
| Val 517 | - | expression tag |
| Pro 518 | - | expression tag |
| Arg 519 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115924.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 422.3 | |
| All* | Total formula weight | 116347.0 |
