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6XWD

14-3-3 sigma bound to canonical mono-phosphorylated aminopeptidase N (APN, CD13) binding motif

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23626542.91UniProt (P31947)
Pfam (PF00244)
Homo sapiens (Human)Epithelial cell marker protein 1,Stratifin
2B
(P)
Amino peptidase N 38-46polymer91011.01UniProt (by SIFTS) (P15144)Homo sapiens
3C, D
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
4E
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
5F, G
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
6H, I
(A, P)
waterwater18.0419Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Gly -4-expression tag
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27553.9
Non-Polymers*Number of molecules5
Total formula weight134.7
All*Total formula weight27688.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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