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6XVP

Crystal structure of Neprilysin in complex with Sampatrilat.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Neprilysinpolymer69979918.91UniProt (P08473)
Pfam (PF05649)
Pfam (PF01431)
Homo sapiens (Human)Atriopeptidase,Common acute lymphocytic leukemia antigen,CALLA,Enkephalinase,Neutral endopeptidase 24.11,Neutral endopeptidase,Skin fibroblast elastase,SFE
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
Sampatrilatnon-polymer584.71Chemie (D0Z)
4D, E, F, G
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
5H, I, J
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
6K
(A)
waterwater18.039Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight79918.9
Non-Polymers*Number of molecules9
Total formula weight1721.1
All*Total formula weight81640.0
*Water molecules are not included.

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PDB entries from 2025-12-17

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