6XV3
CRYSTAL STRUCTURE OF BRD4-BD1 WITH COMPOUND 3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Bromodomain-containing protein 4 | polymer | 127 | 15099.4 | 4 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (Human) | Protein HUNK1 |
| 2 | A, B, C, D | 3-methyl-6-[6-[(3~{S})-3-methylmorpholin-4-yl]-1-[(1~{S})-1-phenylethyl]imidazo[4,5-c]pyridin-2-yl]-~{N}-propan-2-yl-[1,2,4]triazolo[4,3-a]pyrazin-8-amine | non-polymer | 511.6 | 4 | Chemie (O2B) | |||
| 3 | water | water | 18.0 | 668 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 44 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | - | expression tag |
| Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60397.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2046.5 | |
| All* | Total formula weight | 62444.0 |
