6XUY
Human Sirt6 13-308 in complex with ADP-ribose
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | NAD-dependent protein deacetylase sirtuin-6 | polymer | 302 | 33631.6 | 2 | UniProt (Q8N6T7) Pfam (PF02146) | Homo sapiens (Human) | Regulatory protein SIR2 homolog 6,SIR2-like protein 6 |
| 2 | C, K (A, B) | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 2 | Chemie (AR6) PubChem (192) PubChem (25113622) PubChem (25113623) PubChem (445794) PubChem (44415180) PubChem (447048) PubChem (44144391) PubChem (51051599) PubChem (33576) PubChem (89379870) PubChem (91746164) PubChem (447165) PubChem (448826) PubChem (10437766) PubChem (9548001) PubChem (9547960) PubChem (122606931) PubChem (122609061) PubChem (140853820) PubChem (146879505) PubChem (162774256) PubChem (162782217) PubChem (174159053) PubChem (163972867) PubChem (173750345) PubChem (173750346) PubChem (175675949) | |||
| 3 | D, L (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 5 | F, G, H, I, J... (A, B) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) | |||
| 6 | Q, R (A, B) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A, B: 13 - 308 (UniProt: Q8N6T7)
| PDB | External Database | Details |
|---|---|---|
| Gly 7 | - | expression tag |
| Ile 8 | - | expression tag |
| Asp 9 | - | expression tag |
| Pro 10 | - | expression tag |
| Phe 11 | - | expression tag |
| Thr 12 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67263.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2264.2 | |
| All* | Total formula weight | 69527.4 |
